This Act may be cited as the Protecting Life and Integrity in Research Act of 2025.

(a) In general (1) In general No Federal department, agency, or office may conduct, fund, approve, or otherwise support any research involving human fetal tissue that is obtained pursuant to an induced abortion. (2) Development of new, ethical cell lines Subsection (a) does not limit the authority of any Federal department, agency, or office to develop or support the development of new, high-efficiency cell lines, including for the production of vaccines and genetic vectors, so long as the cell lines are not derived from human fetal tissue that is obtained pursuant to an induced abortion. (3) Research involving human fetal tissue obtained after a miscarriage or stillbirth permitted Any research of any Federal department, agency, or office on human fetal tissue obtained after a miscarriage or stillbirth shall be conducted or supported in accordance with section 498A of the Public Health Service Act (42 U.S.C. 289gU.S. Code — Title 42, Section 289gView official source on GovInfo–1). (b) Amendments to the PHSA limiting human fetal tissue research to tissue obtained after a miscarriage or stillbirth Section 498A of the Public Health Service Act (42 U.S.C. 289gU.S. Code — Title 42, Section 289gView official source on GovInfo–1) is amended— (1) in the section heading, by striking transplantation of fetal tissue and inserting human fetal tissue obtained after a miscarriage or stillbirth; (2) by amending subsection (a) to read as follows: (a) Establishment of program The Secretary may conduct or support research on human fetal tissue obtained after a miscarriage or a stillbirth.; (3) in subsection (b)— (A) in paragraph (1)(B), by inserting if the human fetal tissue is intended for transplantation, before the donation; and (B) in paragraph (2)— (i) by striking subparagraph (A); and (ii) by redesignating subparagraphs (B) and (C) as (A) and (B), respectively; (4) in subsection (c)(1)(B), by striking pursuant to a spontaneous or induced abortion or pursuant to and inserting after a miscarriage or; and (5) by amending subsection (g) to read as follows: (g) Definitions In this section: (1) Human fetal tissue The term human fetal tissue means tissue or cells obtained from a dead unborn child pursuant to an induced abortion, a miscarriage, or a stillbirth. (2) Miscarriage The term miscarriage means the involuntary death of an unborn child who was carried in the womb for a period of less than 20 weeks. (3) Stillbirth The term stillbirth means the involuntary death of an unborn child who was carried in the womb for a period of 20 weeks or more. (4) Unborn child The term unborn child has the meaning given such term in section 1841(d) of title 18, United States Code.. (c) Conforming repeal Section 113 of the National Institutes of Health Revitalization Act of 1993 (42 U.S.C. 289gU.S. Code — Title 42, Section 289gView official source on GovInfo–1 note) is repealed.

(a) In general Section 498B(c)(1) of the Public Health Service Act (42 U.S.C. 289gU.S. Code — Title 42, Section 289gView official source on GovInfo–2(c)(1)) is amended to read as follows: (1) solicit or knowingly acquire, receive, or accept a donation (excluding any transfer for purposes of autopsy or burial) of human fetal tissue knowing that— (A) a human pregnancy was deliberately initiated to provide such tissue; or (B) the tissue was obtained pursuant to an induced abortion; or. (b) Conforming changes Section 498B of the Public Health Service Act (42 U.S.C. 289gU.S. Code — Title 42, Section 289gView official source on GovInfo–2), as amended by subsection (a), is further amended— (1) by striking subsection (b); (2) by redesignating subsections (c) through (e) as subsections (b) through (d), respectively; and (3) in subsection (c), as redesignated— (A) in paragraph (1), by striking (a), (b), or (c) and inserting (a) or (b); and (B) in paragraph (2), by striking or (b)(3).