This Act may be cited as the No IRIS Act of 2025.

Notwithstanding any other provision of law, the Administrator of the Environmental Protection Agency may not use any assessment generated by the Integrated Risk Information System program of the Environmental Protection Agency as a basis— (1) to develop, finalize, or issue a rule or regulation; (2) to carry out any other regulatory, enforcement, or permitting action; or (3) to inform air toxics assessments or other mapping or screening tools.